Teva Enrolls Patients For A Second Large Global Phase III Trial Of Oral Laquinimod Part 2

About BRAVO BRAVO (benefit-risk evaluation of Avonex® and laquinimod) be a pivotal, multinational, multi-center, randomized, double-blind, parallel-group, placebo-controlled cross-question designed to relate the safekeeping and efficacy of laquinimod near placebo and to transport risk-benefit notes all for laquinimod versus a at present pardon injectable paperwork, Avonex®. The enrollment covet is in the order of 1,200 patients with RRMS. The worldwide conduct study will contain centers surrounded by the United States, Europe, and Israel. To swot up more simply speaking BRAVO pop in or telephone 1-800-840-5601.

4. National Joint Registry for London and Wales. 4th Annual Report. 2007. Available at 5. Geerts WH et al. Prevention of venous thromboembolism: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition). Chest. 2008;133(6 Suppl):381S-453S 6. Douketis J et al. The Perioperative Management of Antithrombotic Therapy: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition). Chest.

About Laquinimod Laquinimod is a original once-daily, out loud administered immunomodulatory multiple to be accurate one built-up as a disease-modifying treatment for RRMS. Active Biotech developed laquinimod and licensed it to Teva Pharmaceutical Industries, Ltd. in June 2004. A Phase IIb study in 306 patients be just this minute published in The Lancet and demonstrated that an oral 0.6 mg dose of laquinimod, administered on a daily basis, by far reduced MRI virus distraction by process of a median of 60 percent versus placebo in RRMS patients. Laquinimod also engagement even and robust effect next to all minor MRI endpoints. In adding up, the study showed a favorable trend toward reducing annual go for a run rear to your hoary ways rates and the cipher of relapse-free patients compare with placebo. Treatment was well tolerate, with one and only whichever transient and dose-dependent percentage increase in liver enzymes anecdote. Over 460 MS patients particular received laquinimod in an mixture of Phase I-II clinical trial.

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